Education
- PhD in Bioengineering
- Master Degree in Mechanical Engineering
Academic Appointments
- 2013 – 2018: Director of the Biomedical Engineering Programme Council at Politecnico di Milano, and member of the Board of the School of Industrial and Information Engineering at the same Politecnico
- Since mid 鈥�90s: Director of the Artificial Organs Laboratory, part of the Biological Structures Mechanics (LaBS) Laboratory at Politecnico di Milano, coordinating research, consulting and teaching activities
- Member of the PhD in Bioengineering Board, at Politecnico di Milano activities
Membership and Affiliations
- Member of the European Society of Artificial Organs (ESAO)
- Member of the American Society for Artificial Internal Organs (ASAIO)
- Member of the European Society of Biomechanics (ESB)
- Member of the National Bioengineering Society (GNB)
Other
- 2007 – 2013: Project leader or partner in Research projects totally funded or co-funded by private or public institutions. Worth to be mentioned is the Research project 鈥淒ialysIS (Dialysis therapy between Italy and Switzerland)鈥� framed in the INTERREG Funding Programme Italy 鈥� Switzerland
- Responsible of research or consulting contracts with Italian, European or American Companies in the biomedical field
- Co-Holder of European Patents about biomedical devices
- Reviewer for International Journals among which The International Journal of Artificial Organs, ASAIO Journal, Artificial Organs, ASME Journal, Journal of Applied Biomaterials and Biomechanics, Journal of Biomechanics
The research activity is framed in the field of Industrial Bioengineering (both theoretical and experimental) focussing:
- Mass and energy transfer, and fluid dynamics in the biological system and artificial organs through both mathematical and numerical modelling, and experimental evaluation.
- Machine to patient interaction modelling.
- Patient-specific modelling, based on the structured analysis of clinical data, aimed at optimising the single patient reaction to the treatment.
- Design and experimental testing of biomedical devices (e.g. ventricular assist devices, dialysis filters and systems, blood oxygenators, pumping systems, heart valve prostheses, extracorporeal circuits components, liquid ventilation for pre-mature and neonates, etc.);
- Development of novel controlled drug release systems.
- Possenti L., Casagrande G, Di Gregorio S., Zunino P., Costantino ML (2019). . DOI:10.1016/j.mvr.2018.11.003. MICROVASCULAR RESEARCH, vol. 122, p. 101-110, ISSN: 0026-2862.
- Piergiovanni M., Casagrande G., Taverna F., Corridori I., Frigerio M., Bianchi E., Arienti F., Mazzocchi A., Dubini G., Costantino ML (2019). . DOI:10.1007/s10439-019-02342-w. ANNALS OF BIOMEDICAL ENGINEERING, vol. 2019 Aug 13, p. 1-11, ISSN: 0090-6964.
- Bianchi C., Lanzarone E., Casagrande G., Costantino ML (2018). . DOI:10.1177/0962280217745572. STATISTICAL METHODS IN MEDICAL RESEARCH, p. 1-27, ISSN: 0962-2802.
- Luraghi G., Wu Wei, De Gaetano F., Rodriguez M., Jose F., Moggridge Geoff D., Serrani M., Stasiak J., Costantino ML, Migliavacca F. (2017). DOI:10.1016/j.jbiomech.2017.04.004. JOURNAL OF BIOMECHANICS, vol. 58, p. 45-51, ISSN: 0021-9290.
- Casagrande G., Bianchi C., Vito D., Carfagna F., Minoretti C., Pontoriero G., Rombol脿 G., Schoenholzer C., Costantino ML (2016). . DOI:10.5301/ijao.5000504. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, vol. 39 (5), pp.220-227, ISSN:0391-3988.