Education
- 2012: PhD at the University of Cambridge, UK
Academic Appointments
- 2023 – present: Associate Professor at 麻豆传媒AV在线看 University
- 2019: She started her research group at the University of Bern, Switzerland
- 2016 – 2018: Research associate at the University of Basel, Switzerland
- 2012: Post-doctoral fellowship at the Institute of Cancer Research, London, UK
Other
- 2013: Relocated with the lab to Memorial Sloan-Kettering Cancer Center, New York, US
Charlotte鈥檚 work focuses on using multiomics profiling, bioinformatics and computational biology to address outstanding questions and challenges in precision oncology. With many years of experience working with multi-omics data, she is interested in leveraging the abundance of 鈥榦mics鈥� data derived from clinically annotated samples in computational frameworks to advance our understanding in tumor cellular dynamics, to discover novel biomarkers and therapeutic targets and to elucidate genotype-to-phenotype associations in cancer. She has developed automated and reproducible sequencing data analysis pipelines, which have been used in 60+ of her own research publications. She is currently active in the International Cancer Genome Consortium (ICGC-ARGO) Data Coordination and Management Working Group, and contributed to European Society for Medical Oncology (ESMO) Translational Research and Personalised Medicine Working Groups and The Cancer Genome Atlas (TCGA) analysis working group. Her current research projects incorporate state-of-the-art single-cell gene expression profiling and spatial transcriptomics to understand tumor cellular composition and dynamics.
- Kashani E, Schnidrig D, Gheinani AH, Ninck MS, Zens P, Maragkou T, Baumgartner U, Schucht P, R盲tsch G, Rubin MA, SOCIBP consortium, Berezowska S, Ng CKY, Vassella E. . Neuro-oncol. 25(4):662-673 (2023).
- Ng CKY, Dazert E, Boldanova T, Coto-Llerena M, Nuciforo S, Ercan C, Suslov A, Meier MA, Bock T, Schmidt A, Ketterer S, Wang X, Wieland S, Matter MS, Colombi M, Piscuoglio S, Terracciano LM, Hall MN, Heim MH. . Nature Commun. 13(1):2436 (2022).
- Montazeri H, Coto-Llerena M, Bianco G, Zangene E, Taha-Mehlitz S, Paradiso V, Srivatsa S, de Weck A, Roma G, Lanzafame M, Bolli M, Beerenwinkel N, von Fl眉e M, Terracciano LM, Piscuoglio S, Ng CKY. . Nucleic Acid Res. 49(15):8488-8504 (2021).
- Bertucci F*, Ng CKY*, Patsouris A*, Droin N, Piscuoglio S, Carbuccia N, Soria JC, Dien AT, Adnani Y, Kamal M, Garnier S, Meurice G, Jimenez M, Dogan S, Verret B, Chaffanet M, Bachelot T, Campone M, Lefeuvre C, Bonnefoi H, Dalenc F, Jacquet A, De Filippo MR, Babbar N, Birnbaum D, Filleron T, Le Tourneau C, Andr茅 F. . 569(7757):560鈥�564 (2019).
- Ng CKY, Di Costanzo GG, Tosti N, Paradiso V, Coto-Llerena M, Roscigno G, Perrina V, Quintavalle C, Boldanova T, Wieland S, Marino-Marsilia G, Lanzafame M, Quagliata L, Condorelli G, Matter MS, Tortora R, Heim MH, Terracciano LM, Piscuoglio S. . Ann Oncol. 29(5):1286鈥�1291 (2018).