Education
- 1990: Degree in Veterinary Medicine, Universit脿 degli Studi di Milano, Milan
Academic Appointments
- 2017 – present: Associate Professor of Clinical Pathology, 麻豆传媒AV在线看 University, Rozzano, Milan
- 2015 – present: Adjunct Professor of Medical Microbiology, 麻豆传媒AV在线看 University
- 2005 – present: Head of the Laboratory of Experimental Immunopathology, Dept. of Research in Immunology, 麻豆传媒AV在线看 Clinical and Research Hospital, Rozzano, Milan
- 2004 – 2005: Unit Head (Experimental Immunopathology), Laboratory of Immunology, Istituto di Ricerche Farmacologiche 鈥淢ario Negri鈥�, Milan
- 1996 – 2004: Research assistant
- 1994 – 1995: Visiting fellow, D茅partement de Biologie Mol茅culaire et Structurale – Unit茅 INSERM 217 – Centre d’Etudes Nucl茅aires de Grenoble, France
- 1991 – 1994: Research assistant, Immunology Lab, Istituto di Ricerche Farmacologiche 鈥淢ario Negri鈥�, Milan
My expertise is related to innate immunity and regulation of inflammatory responses. My activity has been focused on the functional characterization of original molecules of the immune system, in particular of the long pentraxin PTX3 in innate immune responses to pathogens of fungal, bacterial or viral origin, and in the regulation of inflammatory responses in conditions of infections or tissue damage, such as wound healing and cancer. I contributed to characterize the diagnostic potential of PTX3 in human inflammatory diseases and I am now involved in the translation of PTX3 to the clinic as therapeutic and diagnostic tool in infectious diseases. I also focused on IL-1R8/SIGIRR, a member of the family of IL-1 Receptors and Toll Like Receptors, acting as a negative regulator of inflammatory and immune responses triggered by TLR engagement and by IL-1 family members, in the context of inflammatory diseases, infections, autoimmunity and cancer.
- Garlanda C.,聽Hirsch E., Bozza S., Salustri A., De Acetis M., Nota R., Maccagno A., Riva F., Bottazzi B., Peri G., Doni A., Vago L., Botto M., De Santis R., Carminati P., Siracusa G., Altruda F., Vecchi A., Romani L. and Mantovani A. 鈥撀犅燦ature. 420: 182-186, 2002.
- Garlanda C., Dinarello C. A. and Mantovani A. 鈥撀�聽Immunity. 39: 6, 1003-18, 2013.
- Jaillon S., Moalli F., Ragnarsdottir B., Bonavita E., Puthia M., Riva F., Barbati E., Nebuloni M., Cvetko Krajinovic L., Markotic A., Valentino S., Doni A., Tartari S., Graziani G., Montanelli A., Delneste Y., Svanborg C.,聽Garlanda C.聽and Mantovani A. 鈥�.聽Immunity. 40: 4, 621-32, 2014.
- Bonavita E., Gentile S., Rubino M., Maina V., Papait R., Kunderfranco P., Greco C., Feruglio F., Molgora M., Laface I., Tartari S., Doni A., Pasqualini F., Barbati E., Basso G., Galdiero M. R., Nebuloni M., Roncalli M., Colombo P., Laghi L., Lambris J. D., Jaillon S.,聽Garlanda C.* and Mantovani A.* 鈥撀燙ell. 160: 4, 700-14, 2015.
- Doni A., Musso T., Morone D., Bastone A., Zambelli V., Sironi M., Castagnoli C., Cambieri I., Stravalaci M., Pasqualini F., Laface I., Valentino S., Tartari S., Ponzetta A., Maina V., Barbieri S. S., Tremoli E., Catapano A. L., Norata G. D., Bottazzi B.,聽Garlanda C.聽and Mantovani A. 鈥�. J Exp Med. 212: 6, 905-25, 2015.