{"id":11482,"date":"2019-07-29T05:47:11","date_gmt":"2019-07-29T05:47:11","guid":{"rendered":"http:\/\/hunimed-new.local\/Member\/rosanna-asselta-2\/"},"modified":"2026-03-30T09:24:30","modified_gmt":"2026-03-30T09:24:30","slug":"rosanna-asselta","status":"publish","type":"member","link":"https:\/\/www.hunimed.eu\/it\/member\/rosanna-asselta\/","title":{"rendered":"Rosanna Asselta"},"content":{"rendered":"\n<div class=\"wp-block-hunimed-tabs-content hunimed-tabs-content-block\"><div class=\"tabs-container\">\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Biosketch\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Biosketch<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<p class=\"wp-block-paragraph\"><strong>Formazione<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dottorato di Ricerca in Genetica Molecolare applicata alle Scienze Mediche, Universit\u00e0 degli Studi di Milano<\/li>\n\n\n\n<li>Laurea in Scienze Biologiche, Universit\u00e0 degli Studi di Milano<\/li>\n\n\n\n<li>Acquisizione di una solida competenza in analisi statistica dei dati genetici attraverso: 1. Esperienza di ricerca della durata di due anni presso il Dipartimento di Medicina Molecolare, University of Helsinki 2. Attivit\u00e0 di ricerca presso il Broad Institute of Harvard and MIT, Boston<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Formazione Avanzata e Corsi<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2009<\/strong>: Dana-Farber Cancer Institute, corso di formazione avanzata<\/li>\n\n\n\n<li><strong>2008<\/strong>: Cold Spring Harbor Laboratory, corso di formazione avanzata<\/li>\n\n\n\n<li><strong>2006<\/strong>: University of Helsinki, corso di formazione avanzata<\/li>\n\n\n\n<li><strong>2005<\/strong>: European School of Genetic Medicine, corso di formazione avanzata<\/li>\n\n\n\n<li><strong>2004<\/strong>: Turku Centre for Biotechnology, corso di formazione avanzata<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Incarichi Accademici<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2014 &#8211; presente<\/strong>: Professore Ordinario di Genetica Medica, 麻豆传媒AV在线看 University<\/li>\n\n\n\n<li><strong>2005<\/strong>: Ricercatore in Biologia Molecolare, Facolt\u00e0 di Medicina, Universit\u00e0 degli Studi di Milano<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Premi e Onorificenze<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2005<\/strong>: Early Career Investigator Award (Bayer Hemophilia Program)<\/li>\n\n\n\n<li><strong>2004<\/strong>: Premio della European Molecular Biology Organization (EMBO)<\/li>\n\n\n\n<li><strong>2004<\/strong>: Premio della European Science Foundation<\/li>\n\n\n\n<li><strong>2001<\/strong>: Premio della Fondazione Telethon<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Ricerca\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Ricerca<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<p class=\"wp-block-paragraph\">L\u2019attivit\u00e0 scientifica della prof.ssa Rosanna Asselta si \u00e8 concentrata sullo studio delle basi genetico-molecolari di malattie ereditarie umane, sia monogeniche che multifattoriali.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In particolare, negli ultimi cinque anni, la Prof. Asselta si \u00e8 dedicata allo studio di:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>meccanismi molecolari responsabili di alcune coagulopatie emorragiche rare (afibrinogenemia, carenza congenita di fattore V e XI della coagulazione);<\/li>\n\n\n\n<li>Studio dei determinanti genetici di suscettibilit\u00e0 ad alcune malattie complesse (infarto del miocardio giovanile, sclerosi multipla e malattia di Parkinson).<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Pubblicazioni\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Pubblicazioni<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<ol class=\"wp-block-list\">\n<li>Cardamone G, Paraboschi EM, Sold\u00e0 G, Cantoni C, Supino D, Piccio L, Duga S, <strong><u>Asselta R<\/u><\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30566690\/\">Not only cancer: the long non-coding RNA MALAT1 affects the repertoire of alternatively spliced transcripts and circular RNAs in multiple sclerosis<\/a>. Hum Mol Genet. 2019; 28:1414-1428.<\/li>\n\n\n\n<li><strong><u>Asselta R<\/u><\/strong>, Paraboschi EM, Rimoldi V, Menegatti M, Peyvandi F, Salomon O, Duga S. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28615222\/\">Exploring the global landscape of genetic variation in coagulation factor XI deficiency<\/a>. Blood. 2017; 130:e1-e6.<\/li>\n\n\n\n<li><strong><u>Asselta R<\/u><\/strong>, Rimoldi V, Siri C, Cilia R, Guella I, Tesei S, Sold\u00e0 G, Pezzoli G, Duga S, Goldwurm S. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25249066\/\">Glucocerebrosidase mutations in primary parkinsonism<\/a>. Parkinsonism Relat Disord. 2014; 20:1215-20<\/li>\n\n\n\n<li>Do R, Stitziel NO, Won HH, J\u00f8rgensen AB, Duga S, Angelica Merlini P, Kiezun A, Farrall M, Goel A, Zuk O, Guella I, <strong><u>Asselta R<\/u><\/strong>, Lange LA, Peloso GM, Auer PL; NHLBI Exome Sequencing Project, Girelli D, Martinelli N, Farlow DN, DePristo MA, Roberts R, Stewart AF, Saleheen D, Danesh J, Epstein SE, Sivapalaratnam S, Kees Hovingh G, Kastelein JJ, Samani NJ, Schunkert H, Erdmann J, Shah SH, Kraus WE, Davies R, Nikpay M, Johansen CT, Wang J, Hegele RA, Hechter E, Marz W, Kleber ME, Huang J, Johnson AD, Li M, Burke GL, Gross M, Liu Y, Assimes TL, Heiss G, Lange EM, Folsom AR, Taylor HA, Olivieri O, Hamsten A, Clarke R, Reilly DF, Yin W, Rivas MA, Donnelly P, Rossouw JE, Psaty BM, Herrington DM, Wilson JG, Rich SS, Bamshad MJ, Tracy RP, Adrienne Cupples L, Rader DJ, Reilly MP, Spertus JA, Cresci S, Hartiala J, Wilson Tang WH, Hazen SL, Allayee H, Reiner AP, Carlson CS, Kooperberg C, Jackson RD, Boerwinkle E, Lander ES, Schwartz SM, Siscovick DS, McPherson R, Tybjaerg-Hansen A, Abecasis GR, Watkins H, Nickerson DA, Ardissino D, Sunyaev SR, O\u2019Donnell CJ, Altshuler D, Gabriel S, Kathiresan S. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25487149\/\">Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction<\/a>. Nature. 2015; 518:102-6.<\/li>\n\n\n\n<li>TG and HDL Working Group of the Exome Sequencing Project, National Heart, Lung, and Blood Institute, Crosby J, Peloso GM, Auer PL, Crosslin DR, Stitziel NO, Lange LA, Lu Y, Tang ZZ, Zhang H, Hindy G, Masca N, Stirrups K, Kanoni S, Do\u00a0 R, Jun G, Hu Y, Kang HM, Xue C, Goel A, Farrall M, Duga S, Merlini PA, <strong><u>Asselta R<\/u><\/strong>, Girelli D, Olivieri O, Martinelli N, Yin W, Reilly D, Speliotes E, Fox CS, Hveem K, Holmen OL, Nikpay M, Farlow DN, Assimes TL, Franceschini N, Robinson J, North KE, Martin LW, DePristo M, Gupta N, Escher SA, Jansson JH, Van Zuydam N, Palmer CN, Wareham N, Koch W, Meitinger T, Peters A, Lieb W, Erbel R, Konig IR, Kruppa J, Degenhardt F, Gottesman O, Bottinger EP, O&#8217;Donnell CJ, Psaty BM, Ballantyne CM, Abecasis G, Ordovas JM, Melander O, Watkins H, Orho-Melander M, Ardissino D, Loos RJ, McPherson R, Willer CJ, Erdmann J, Hall AS, Samani NJ, Deloukas P, Schunkert H, Wilson JG, Kooperberg C, Rich SS, Tracy RP, Lin DY, Altshuler D, Gabriel S, Nickerson DA, Jarvik GP, Cupples LA, Reiner AP, Boerwinkle E, Kathiresan S. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24941081\/\">Loss-of-function mutations in APOC3, triglycerides, and coronary disease<\/a>. N Engl J Med. 2014; 371:22-31.<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":32628,"template":"","departaments":[262,313],"roles":[203,206],"class_list":["post-11482","member","type-member","status-publish","has-post-thumbnail","hentry","departament-genetica-medica-2","departament-genetica-medica-3","role-full-professor-it","role-professore-ordinario"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Rosanna Asselta - Hunimed<\/title>\n<meta name=\"description\" content=\"Biosketch Formazione Dottorato di Ricerca in Genetica Molecolare applicata alle Scienze Mediche, Universit\u00e0 degli Studi di Milano Laurea in Scienze\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hunimed.eu\/it\/member\/rosanna-asselta\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Rosanna Asselta - 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