{"id":11470,"date":"2019-09-16T09:16:03","date_gmt":"2019-09-16T09:16:03","guid":{"rendered":"http:\/\/hunimed-new.local\/Member\/luca-di-tommaso\/"},"modified":"2026-03-31T10:30:59","modified_gmt":"2026-03-31T10:30:59","slug":"luca-di-tommaso","status":"publish","type":"member","link":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/","title":{"rendered":"Luca Di Tommaso"},"content":{"rendered":"\n<div class=\"wp-block-hunimed-tabs-content hunimed-tabs-content-block\"><div class=\"tabs-container\">\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Biosketch\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Biosketch<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<p><strong>Formazione<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2014<\/strong>: Fellowship, International Academy of Cytology<\/li>\n\n\n\n<li><strong>2003<\/strong>: Specializzazione in Anatomia Patologica, Universit\u00e0 di Bologna<\/li>\n\n\n\n<li><strong>1997<\/strong>: Laurea in Medicina e Chirurgia, <em>summa cum laude<\/em>, Universit\u00e0 di Bologna<\/li>\n<\/ul>\n\n\n\n<p><strong>Incarichi Accademici<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Professore Associato di Anatomia Patologica, 麻豆传媒AV在线看 University<\/li>\n\n\n\n<li>Insegnamenti &#8211; Scuola di Specializzazione in Anatomia Patologica e Corso di Laurea in Medicina e Chirurgia: Corso di Istologia (1\u00b0 anno) | Corso di Storia della Medicina (1\u00b0 anno) | Corso di Fondamenti in Anatomia Patologica (3<sup>\u00b0&nbsp;<\/sup>anno) | Corso di Sistematica 1 (3<sup>\u00b0&nbsp;<\/sup>anno) | Corso di Anatomia Patologica (4<sup>\u00b0<\/sup>&nbsp;anno), 麻豆传媒AV在线看 University<\/li>\n\n\n\n<li><strong>2021 &#8211; presente<\/strong>: Membro della Commissione Riesame, 麻豆传媒AV在线看 University<\/li>\n\n\n\n<li><strong>2014 &#8211; presente<\/strong>: Fellow, International Academy of Cytology<\/li>\n\n\n\n<li><strong>2015 &#8211; 2021<\/strong>: Ricercatore Universitario di Anatomia Patologica, C.d.L. in Medicina e Chirurgia, 麻豆传媒AV在线看 University<\/li>\n\n\n\n<li><strong>2016 &#8211; 2020<\/strong>: Membro del Senato Accademico, 麻豆传媒AV在线看 University<\/li>\n\n\n\n<li><strong>2012 &#8211; 2015<\/strong>: Ricercatore Universitario di Anatomia Patologica, C.d.L. in Medicina e Chirurgia, Universit\u00e0 di Milano<\/li>\n\n\n\n<li><strong>2004 &#8211; 2012<\/strong>: Professore a contratto di Anatomia Patologica, C.d.L. in Medicina e Chirurgia, Universit\u00e0 di Milano<\/li>\n<\/ul>\n\n\n\n<p><strong>Affiliazioni<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>International Academy of Cytology (IAC)<\/li>\n\n\n\n<li>International Liver Cancer Association (ILCA)<\/li>\n\n\n\n<li>Laennec Liver Pathology Society<\/li>\n<\/ul>\n\n\n\n<p><strong>Premi e Onorificenze<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>2020<\/strong>: Progetto di ricerca \u201cDissecting the role of Tumor Endothelial Cells in HCC with VETC+ angiogenesis provides potential targets of treatment\u201d; AIRC Investigator Grant (IG 2020 ID 25087); PI: Luca Di Tommaso<\/li>\n\n\n\n<li><strong>2018<\/strong>: Progetto di Ricerca \u201cApPath: a tool of augmented pathology to evaluate the immune texture in metastatic colorectal cancer\u201d; Fondazione 麻豆传媒AV在线看 per la ricerca (Fondi 5 per 1000); PI: Luca Di Tommaso<\/li>\n\n\n\n<li><strong>2018<\/strong>: Progetto di ricerca \u201cValutazione del microscopio NED-DP\u201d; Nano Tech Project; PI: Luca Di Tommaso<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Ricerca\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Ricerca<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<p>Il mio principale ambito di ricerca \u00e8 rappresentato dalla patologia Epatica. I miei primi studi sono stati focalizzati sulla caratterizzazione morfologica, fenotipica e molecolare della epatocarcinogenesi (in particolare le lesioni preneoplastiche e neoplastiche iniziali, vedi pubblicazioni selezionate 1 e 2).\n\nSuccessivamente mi sono interessato di prognosi delle forme avanzate di carcinoma epato- e colangio- cellulare (PLC, Primary Liver Cancer). Quanto sin qui menzionato aveva come aspetto centrale lo studio della cellula neoplastica. Pi\u00f9 di recente il mio studio si \u00e8 focalizzato sul microambiente tumorale sia dei PLC che delle metastasi epatiche, in particolare l\u2019ambito delle Tumoral Endothelia Cells (TEC, vedi pubblicazione selezionata 3).\n\nAltri ambiti di ricerca di cui mi occupo sono quello della patologia mammaria, timica e tiroidea: in ciascuno di questi ho contribuito ad identificare nuove entit\u00e0 nosologiche (a titolo di esempio la variet\u00e0 adenoideo-cistica del carcinoma timico).\n\nMi interesso con passione di Storia della Medicina: questa ultima, insieme alla Anatomia Patologica, sono le due discipline che insegno presso 麻豆传媒AV在线看 University. L\u2019obiettivo della mia ricerca \u00e8 sempre stato e continua ad essere quello di identificare marcatori di diagnosi, prognosi e predizione di risposta alla terapia. In questo contesto, recentissimamente, mi sono avvicinato allo studio della patologia digitale, computazionale ed \u201caumentata\u201d (vedi pubblicazioni selezionate 4 e 5). Questi ambiti che, nel loro insieme, definiscono la cosiddetta e-Pathology meglio rappresentano lo scenario futuro della mai ricerca e, verosimilmente, la principale ricaduta traslazionale della stessa.\n\n&nbsp;<\/p>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-hunimed-tabs-content-tab tabs-content-tab\"><div class=\"tab-item\" data-tab-title=\"Pubblicazioni\"><div class=\"tab-header\"><button class=\"tab-nav\" role=\"tab\" aria-selected=\"false\"><span class=\"tab-title\">Pubblicazioni<\/span><\/button><\/div><div class=\"tab-content\" role=\"tabpanel\" aria-hidden=\"true\">\n<ol class=\"wp-block-list\">\n<li><strong>Di Tommaso L<\/strong>, Franchi G, Park NY, Fiamengo B, Destro A, Morenghi E, Montorsi M, Torzilli G, Tommasini M, Terracciano L, Tornillo L, Vecchione R, Roncalli M. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17326147\/\">Diagnostic value of HSP70, glypican 3 and glutamine synthetase in hepatocellular nodules in cirrhosis<\/a>. <em>Hepatology 2007; 45(3): 725-735<\/em><\/li>\n\n\n\n<li><strong>Di Tommaso L<\/strong>, Destro A, Seok JY, Balladore E, Terracciano L, Sangiovanni A, Iavarone M, Colombo M, Jang JJ, Yu E, Jin SY, marenghi M, Park YN, Roncalli M. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19231003\/\">The application of a panel of markers (HSP 70, GPC3, GS) in liver biopsies is useful for HCC detection<\/a>. <em>Journal of Hepatology 2009; 50(4): 746-54<\/em><\/li>\n\n\n\n<li>RenneSL, WooHY, AllegraA, Rudini N, YanoH, Donadon M, Vigan\u00f2L, AkibaJ, LeeHS, RheeH, ParkYN, RoncalliM, <strong>Di Tommaso L<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31206715\/\">VETC (vessels encapsulating tumor clusters) is a powerful predictor of aggressive hepatocellular carcinoma<\/a>. <em>2020; 71(1):183-195<\/em><\/li>\n\n\n\n<li>Cancian P, Cortese N, Donadon M, Di Maio M, Soldani C, Marchesi F, Savevski V, Santambrogio MD, Cerina L, Laino ME, Torzilli G, Mantovani A, Terracciano L, Roncalli M, <strong>Di Tommaso L<\/strong>.<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34282750\/\"> Development of a Deep-Learning Pipeline to Recognize and Characterize Macrophages in Colo-Rectal Liver Metastasis<\/a>. Cancers (Basel). 2021; 13(13):3313.<\/li>\n\n\n\n<li>Lancellotti C, Cancian P, Savevski V, Kotha SRR, Fraggetta F, Graziano P, <strong>Di Tommaso L<\/strong>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33918173\/\">Artificial Intelligence &amp; Tissue Biomarkers: Advantages, Risks and Perspectives for Pathology<\/a>. Cells. 2021;10(4):787.<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":32817,"template":"","departaments":[355,142],"roles":[202,212],"class_list":["post-11470","member","type-member","status-publish","has-post-thumbnail","hentry","departament-anatomia-patologica-4","departament-anatomia-patologica-2","role-associate-professor-it","role-professore-associato-2"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Luca Di Tommaso - Hunimed<\/title>\n<meta name=\"description\" content=\"Biosketch Formazione 2014: Fellowship, International Academy of Cytology 2003: Specializzazione in Anatomia Patologica, Universit\u00e0 di Bologna 1997: Laurea\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Luca Di Tommaso - Hunimed\" \/>\n<meta property=\"og:description\" content=\"Biosketch Formazione 2014: Fellowship, International Academy of Cytology 2003: Specializzazione in Anatomia Patologica, Universit\u00e0 di Bologna 1997: Laurea\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/\" \/>\n<meta property=\"og:site_name\" content=\"Hunimed\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Hunimed\/\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-31T10:30:59+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2019\/09\/Di-Tommaso-Luca-7208.jpg?wsr\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"1271\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/\",\"url\":\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/\",\"name\":\"Luca Di Tommaso - Hunimed\",\"isPartOf\":{\"@id\":\"https:\/\/www.hunimed.eu\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2019\/09\/Di-Tommaso-Luca-7208.jpg?wsr\",\"datePublished\":\"2019-09-16T09:16:03+00:00\",\"dateModified\":\"2026-03-31T10:30:59+00:00\",\"description\":\"Biosketch Formazione 2014: Fellowship, International Academy of Cytology 2003: Specializzazione in Anatomia Patologica, Universit\u00e0 di Bologna 1997: Laurea\",\"breadcrumb\":{\"@id\":\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#breadcrumb\"},\"inLanguage\":\"it-IT\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#primaryimage\",\"url\":\"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2019\/09\/Di-Tommaso-Luca-7208.jpg?wsr\",\"contentUrl\":\"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2019\/09\/Di-Tommaso-Luca-7208.jpg?wsr\",\"width\":1000,\"height\":1271},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.hunimed.eu\/it\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Luca Di Tommaso\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.hunimed.eu\/#website\",\"url\":\"https:\/\/www.hunimed.eu\/\",\"name\":\"Hunimed\",\"description\":\"麻豆传媒AV在线看 University\",\"publisher\":{\"@id\":\"https:\/\/www.hunimed.eu\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.hunimed.eu\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"it-IT\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.hunimed.eu\/#organization\",\"name\":\"麻豆传媒AV在线看 University\",\"url\":\"https:\/\/www.hunimed.eu\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"it-IT\",\"@id\":\"https:\/\/www.hunimed.eu\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2025\/06\/Logo.svg?wsr\",\"contentUrl\":\"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2025\/06\/Logo.svg?wsr\",\"caption\":\"麻豆传媒AV在线看 University\"},\"image\":{\"@id\":\"https:\/\/www.hunimed.eu\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/Hunimed\/\",\"https:\/\/www.linkedin.com\/school\/18280267\/admin\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Luca Di Tommaso - Hunimed","description":"Biosketch Formazione 2014: Fellowship, International Academy of Cytology 2003: Specializzazione in Anatomia Patologica, Universit\u00e0 di Bologna 1997: Laurea","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/","og_locale":"it_IT","og_type":"article","og_title":"Luca Di Tommaso - Hunimed","og_description":"Biosketch Formazione 2014: Fellowship, International Academy of Cytology 2003: Specializzazione in Anatomia Patologica, Universit\u00e0 di Bologna 1997: Laurea","og_url":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/","og_site_name":"Hunimed","article_publisher":"https:\/\/www.facebook.com\/Hunimed\/","article_modified_time":"2026-03-31T10:30:59+00:00","og_image":[{"width":1000,"height":1271,"url":"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2019\/09\/Di-Tommaso-Luca-7208.jpg?wsr","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Tempo di lettura stimato":"4 minuti"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/","url":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/","name":"Luca Di Tommaso - Hunimed","isPartOf":{"@id":"https:\/\/www.hunimed.eu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#primaryimage"},"image":{"@id":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#primaryimage"},"thumbnailUrl":"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2019\/09\/Di-Tommaso-Luca-7208.jpg?wsr","datePublished":"2019-09-16T09:16:03+00:00","dateModified":"2026-03-31T10:30:59+00:00","description":"Biosketch Formazione 2014: Fellowship, International Academy of Cytology 2003: Specializzazione in Anatomia Patologica, Universit\u00e0 di Bologna 1997: Laurea","breadcrumb":{"@id":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#breadcrumb"},"inLanguage":"it-IT","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/"]}]},{"@type":"ImageObject","inLanguage":"it-IT","@id":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#primaryimage","url":"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2019\/09\/Di-Tommaso-Luca-7208.jpg?wsr","contentUrl":"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2019\/09\/Di-Tommaso-Luca-7208.jpg?wsr","width":1000,"height":1271},{"@type":"BreadcrumbList","@id":"https:\/\/www.hunimed.eu\/it\/member\/luca-di-tommaso\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.hunimed.eu\/it\/"},{"@type":"ListItem","position":2,"name":"Luca Di Tommaso"}]},{"@type":"WebSite","@id":"https:\/\/www.hunimed.eu\/#website","url":"https:\/\/www.hunimed.eu\/","name":"Hunimed","description":"麻豆传媒AV在线看 University","publisher":{"@id":"https:\/\/www.hunimed.eu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.hunimed.eu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"it-IT"},{"@type":"Organization","@id":"https:\/\/www.hunimed.eu\/#organization","name":"麻豆传媒AV在线看 University","url":"https:\/\/www.hunimed.eu\/","logo":{"@type":"ImageObject","inLanguage":"it-IT","@id":"https:\/\/www.hunimed.eu\/#\/schema\/logo\/image\/","url":"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2025\/06\/Logo.svg?wsr","contentUrl":"https:\/\/www.hunimed.eu\/wp-content\/uploads\/2025\/06\/Logo.svg?wsr","caption":"麻豆传媒AV在线看 University"},"image":{"@id":"https:\/\/www.hunimed.eu\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/Hunimed\/","https:\/\/www.linkedin.com\/school\/18280267\/admin\/"]}]}},"taxonomy_info":{"departament":[{"value":355,"label":"Anatomia Patologica"},{"value":142,"label":"Anatomia Patologica"}],"role":[{"value":202,"label":"Associate Professor"},{"value":212,"label":"Professore Associato"}]},"featured_image_src_large":["https:\/\/www.hunimed.eu\/wp-content\/uploads\/2019\/09\/Di-Tommaso-Luca-7208-806x1024.jpg?wsr",806,1024,true],"author_info":[],"comment_info":"","role":[202,212],"departament":[355,142],"_links":{"self":[{"href":"https:\/\/www.hunimed.eu\/it\/wp-json\/wp\/v2\/members\/11470","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hunimed.eu\/it\/wp-json\/wp\/v2\/members"}],"about":[{"href":"https:\/\/www.hunimed.eu\/it\/wp-json\/wp\/v2\/types\/member"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hunimed.eu\/it\/wp-json\/wp\/v2\/media\/32817"}],"wp:attachment":[{"href":"https:\/\/www.hunimed.eu\/it\/wp-json\/wp\/v2\/media?parent=11470"}],"wp:term":[{"taxonomy":"departament","embeddable":true,"href":"https:\/\/www.hunimed.eu\/it\/wp-json\/wp\/v2\/departaments?post=11470"},{"taxonomy":"role","embeddable":true,"href":"https:\/\/www.hunimed.eu\/it\/wp-json\/wp\/v2\/roles?post=11470"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}